Referencie a štúdie

Aljasir A, Pierson T, Hoffmann G, Menke H. Management of donor site infections in split-thickness skin graft with water-filtered infrared-A (wIRA). Management von Infektionen von Spenderstellen bei Spalthauttransplantationen mittels wassergefiltertem Infrarot A (wIRA). GMS Interdiscip Plast Reconstr Surg DGPW 2018;7:Doc03 (Doi: 10.3205/iprs000123)

König A, Missalla S, Valesky EM, Bernd A, Kaufmann R, Kippenberger S, et al. Effect of NIR photobiomodulation therapy in a cellular wound healing model. Photodermatol Photoimmunol Photomed 2018. Accepted Article (DOI: 10.1111/phpp.12390)

Vaupel P, Piazena H, Müller W, Notter M. Biophysical and photobiological basics of water-filtered infrared-A hyperthermia of superficial tumours. Int J Hyperthermia, 2018, Published online.
(DOI: 10.1080/02656736.2018.1469169)

Hoffmann G. Water-filtered infrared-A (wIRA) overcomes swallowing disorders and hypersalivation – a case report [bilingual]. [Wassergefiltertes Infrarot A (wIRA) überwindet Schluckstörungen und vermehrte Speichelbildung – ein Fallbericht]. GMS Ger Med Sci. 2017;15:Doc11. (DOI: 10.3205/000252)

Piazena. H, Meffert, H and R. Uebelhack: Spectral remittance and transmittance of visible and of infrared-A radiation in human skin Comparison between in vivo measurements and model calculations.- Photochem. Photobiol, 2017, 93: 1449–1461 (DOI: 10.1111/php.12775)

Notter M., Piazena H., Vaupel P. Hypofractionated re-irradiation of large-sized recurrent breast cancer with thermography-controlled, contact-free water-filtered infrared-A hyperthermia: a retrospective study of 73 patients. Int J Hyperthermia 2017, 33/2:227-236 (DOI:10.1080/02656736.2016.1235731)

Ali Al-Ahmad A, Walankiewicz A, Hellwig E, Follo M, Tennert C, WittmerA, Karygianni L. Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (visCwIRA) and Chlorine e6 (Ce6) Eradicates Planktonic Periodontal Pathogens and Subgingival Biofilms. Front Microbiol 2016, 7:1900, (DOI: doi: 10.3389/fmicb.2016.01900)

Rahn C, Marti H, Frohns A, Frohns F, Blenn Ch, Leonard CA, Barisani-Asenbauer T, Stein E Borel N. Water-filtered infrared A reduces chlamydial infectivity in vitro without causing ex vivo eye damage in pig and mouse models. J Photochem Photobiol B. 2016, 165:340-350. doi: 10.1016/j.jphotobiol.2016.11.001. Epub 2016 Nov 5

Zöller N, König A, Butting M, Kaufmann R, Bernd A, Valesky E, Kippenberger S. Water-filtered near-infrared influences collagen synthesis of keloid-fibroblasts in contrast to normal foreskin fibroblasts. J Photochem Photobiol 2016, 163:194-202
(DOI: 10.1016/j.jphotobiol.2016.08.020)

Notter M., Piazena H., Vaupel P. Hypofractionated re-irradiation of large-sized recurrent breast cancer with thermography-controlled, contact-free water-filtered infrared-A hyperthermia: a retrospective study of 73 patients. Int J Hyperthermia. 2016, Sep 12:1-10. [Epub ahead of print] (DOI:10.1080/02656736.2016.1235731)

Hoffmann G, Hartel M, Mercer JB. Heat for wounds – water-filtered infrared-A (wIRA) for wound healing – a review. GMS Ger Med Sci. 2016;14:Doc08. (DOI: 10.3205/000235).

Janssen CW, Lowry CA, Mehl MR, Allen JJ, Kelly KL, Gartner DE, Medrano A, Begay TK, Rentscher K, White JJ, Fridman A, Roberts LJ,Robbins ML, Hanusch KU, Cole SP, Raison CL. Whole-Body Hyperthermia for the Treatment of Major Depressive Disorder: A Randomized Clinical Trial. JAMA Psychiatry 2016; 73/8: 789-795 (Doi: 10.1001/jamapsychiatry.2016.1031)

Rich LJ, Winslow, TB, Alberico RA, Repasky EA, Seshadri M, Singh AK. Enhanced tumour perfusion following treatment with water-filtered IR-A radiation to the thorax in a patient with head and neck cancer. Int J Hyperthermia 2016; 32/5: 539-542.
(DOI: 10.3109/02656736.2016.1167259)

Knels L, Valtink M, Piazena H, Marin JV, Gommel K, Lupp A, Roehlecke C, Mehner M, Funk RH. Effects of Narrow-band IR-A and of Water-filtered Infrared A (wIRA) on Fibroblasts. Photochem Photobiol. 2016 Feb 15 Epub ahead of print. (DOI: 10.1111/php.12579)

Müller W: The Sun’s infrared-A protects the skin. Press Release of AWMF, 02-02-2016. https://idw-online.de/de/news645415

Diffey B, Cadars B. An appraisal of the need for infrared radiation protection in sunscreens. Photochem. Photobiol. Sci., 2016; 15:361-364 (DOI: 10.1039/c5pp00451a)

Barolet D, Christiaens F, Hamblin MR. Infrared and skin: Friend or foe.
J Photochem Photobiol B. 2016; 155:78-85. DOI: 10.1016/j.jphotobiol.2015.12.014)

Däschlein G, Napp M, Söhnel A, von Podewils S, Lutze S, Arnold A, Jünger M. Photodynamic therapy in dermatology: Actual indications and new alternative therapies. Congress report from the First Sino-German Symposium. Photon Lasers Med 2015; 4(4):381–385 (DOI 10.1515/plm-2015-0032)

Marti H, Blenn Ch, Borel N. The contribution of temperature, exposure intensity and visible light to the inhibitory effect of irradiation on acute chlamydial infection. Photochem Photobiol 2015; 153:324-333. (Doi:10.1016/j.jphotobiol.2015.10.012)

Al-Ahmad A, Bucher M, Anderson AC, Tennert C, Hellwig E, Wittmer A, Vach K, Karygianni L. Antimicrobial Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (VIS + wIRA) Alters In Situ Oral Biofilms. PLoS ONE 2015; 10(7): e0132107. (DOI:10.1371/journal.pone.0132107)

KarygianniL, Ruf S, Follo M, Hellwig E, Bucher M, Anderson A, Vach K, Al-Ahmad A: NovelBroad-Spectrum Antimicrobial Photoinactivation of In Situ Oral Biofilms UsingVisible Light Plus Water-Filtered Infrared-A (VIS + wIRA). Applied andEnvironmental Microbiology (AEM) 2014: Published ahead of print 19 September.(DOI: 10.1128/AEM.02490-14)

Giehl KA,Kriz M, Grahovac, Ruzicka T, Berking C. A controlled trial of photodynamictherapy of actinic keratosis comparing different red light sources. Eur J Dermatol2014; 24/3:335-41.
(Doi: 10.1684/ejd.2014.2364.)

Piazena H,Pittermann W, Müller W, Jung K, Kelleher DK, Herrling T, Meffert P, UebelhackR, Kietzmann M: Effects of water-filtered infrared-A and of heat on cell death,inflammation, antioxidative potential and of free radical formation in viableskin – First Results. J Photochem Photobiol 2014; 138: 347-354. (DOI:10.1016/j.jphotobiol.2014.06.007)

Hainfeld JF,Lin L, Slatkin DN, Dilmanian FA, Vadas TM, Smilowitz HM. Gold nanoparticlehyperthermia reduces radiotherapy dose. Nanomedicine: Nanotechnology, Biology,and Medicine 2014; Available online 2 June 2014, in press.

Marti H,Koschwanez M, Pesch T, Blenn Ch, Borel N: Water-Filtered Infrared A Irradiationin Combination with Visible Light Inhibits Acute Chlamydial Infection. PLOS ONE2014; 9(7): e102239. (DOI: 10.1371/journal.pone.0102239)

Jung T, Höhn A, Lau A-M, Piazena H, Grune T: An experimental setup for the measurement of non-thermal effects during water-filtered infrared A (wIRA)-irradiation of mammalian cell cultures. Photochem Photobiol 2012: 88 (2): 371-380 (DOI: 10.1111/j.1751-1097.2011.01072.x)

DaeschleinG, Alborovac J, Patzelt A, Kramer A, Lademann: Kinetics of Physiological Skin Flora in a Suction Blister Wound Model on Healthy Subjects after Treatment with Water-Filtered Infrared-A Radiation. Skin Pharmacol Physiol 2012;25 (2): 73-77 (DOI: 10.1159/000332753)

von Felbert V, Kernland-Lang K, Hoffmann G, Wienert V, Simon D, Hunziker T : Irradiation with water-filtered infrared-A (wIRA) plus visible light improves cutaneous scleroderma lesions in a series of cases. Dermatology 2011: 222: 347–357 (DOI: 10.1159/000329024)

Schumann H, Calow T, Weckesser S, Müller ML, Hoffmann G: Water-filtered infrared-A (wIRA) for the treatment of chronic venous stasis ulcers of the lower legs at home – a randomized controlled blinded study. Br J Dermatol 2011: 165: 541–551. DOI 10.1111/j.1365-2133.2011.10410.x

von Felbert V, Kernland-Lang K, Hoffmann G, Wienert V, Simon D, Hunziker T: Irradiation with water-filtered infrared-A (wIRA) plus visible light improves cutaneous scleroderma lesions in a series of cases. Dermatology 2011. (accepted for publication)

Notter M, Germond JF, Wolf E, Berz R, Berz J: Thermography guided irradiation using water-filtered Infrared-A (wIRA) and radiotherapy on recurrent breast cancer – first experiences and temperature analysis. Thermology International 2011: 21 (2): 47-53

Müller W: The Sun’s infrared-A is not detrimental to the skin. Pressemitteilung der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften AWMF im Informationsdienst Wissenschaft idw, published online http://idw-online.de/en/news379479

von Felbert V, Hoffmann G, Hoff-Lesch S, Abuzahra F, Renn CN, Neugebauer S, Braathen LR, Merk HF: Photodynamic therapy of multiple actinic keratoses: Reduced pain through use of visible light plus water-filtered infrared-A (wIRA) compared to light from light-emitting diodes. Brit J Dermatol 2010: 163/3:607-615, DOI: 10.1111/j.1365-2133.2010.09817.x
Abstract

Piazena H, Kelleher DK: Effects of Infrared-A Irradiation on Skin: Discrepancies in Published Data Highlight the Need for an Exact Consideration of Physical and Photobiological Laws and Appropriate Experimental Settings. Photochem Photobiol 2010: **:*-*, in press,
DOI: 10.1111 ⁄ j.1751-1097.2010.00729.x

Jung T, Höhn A, Piazena H, Grune T: Effects of water-filtered infrared-A (wIRA) irradiation on human fibroblasts. Free Radic Biol Med 2010; 48/1: 153-160, doi:10.1016/j.freeradbiomed.2009.10.036
Abstract

Geißler E und Schumann H: Wassergefiltertes Infrarot A (wIRA) bei ulzerierter Morphea. Water-filtered infrared–A (wIRA) in ulcerated morphea. Z Wundheil. 2009: 14(3): 177-80.

Hoffmann G: Water-filtered infrared-A (wIRA) in acute and chronic wounds [review article]. Wassergefiltertes Infrarot A (wIRA) bei akuten und chronischen Wunden [Übersichtsarbeit].
GMS Krankenhaushyg Interdiszip. 2009;4(2):Doc12. >DOI: 10.3205/dgkh000137< URN: urn:nbn:de:0183-dgkh0001373

Mercer JB, Nielsen SP, Hoffmann G: Improvement of wound healing by water-filtered infrared-A (wIRA) in patients with cronic venous statis ulcers of the lower legs including evaluation using infrared thermography. GMS Ger Med Sci. 2008;6:Doc1
Research Article

Krüger S, Lipski A, Jahr S, Kujath K, Mathiske-Schmidt K, Reißhauer A: Serielle wassergefilterte Infrarot A Bestrahlung mit Fahrradergometrie (Hydrosun®) bei Fibromyalgiepatienten. Phys Med Rehab Kuror 2008; 18: 216 (12)

Wilsmann-Theis D, Bieber T, Novak N: Photodynamic Therapy as an Alternative Treatment for Cutaneous Sarcoidosis. Dermatology 2008; 217: 343-346.
Abstract

Löwe V, Singer D.: Quantitative Thermographie bei Neugeborenen unter verschiedenen Arten von Wärmestrahlung. Z Geburtsh Neonatol 2008; 212: S92, P148, ISSN 1615-5300

Otberg N, Grone D, Meyer L, Schanzer S, Hoffmann G, Ackermann H, Sterry W, Lademann J: Water-filtered infrared-A (wIRA) can act as a penetration enhancer for topically applied substances. Wassergefiltertes Infrarot A (wIRA) kann als Penetrationsverstärker für topisch aufgetragene Substanzen wirken. GMS Ger Med Sci. 2008; 6:Doc08.
Research Article

Hoffmann G: Überblicksarbeit zu wassergefiltertem Infrarot-A (Wira): Klinische Anwendungen von wassergefiltertem Infrarot A (wIRA). In: Kaase H., Serick, F., Hrsg.: Sechstes Symposium „Licht und Gesundheit“.
Eine Sondertagung der Technischen Universität Berlin und der Deutschen Gesellschaft für Photobiologie mit der Deutschen Akadmie für Photobiologie und Phototechnologie und der Deutschen Lichttechnischen Gesellschaft, Berlin, 13./14.03.2008. Berlin; 2008. S. 130-146. ISBN: 3-9807635-0-3.

Hoffmann G: Wassergefiltertes Infrarot A (wIRA) zur Verbesserung der Wundheilung bei aktuen und chronischen Wunden. Water filtered Infrared A (wIRA) for the improvement of wound healing in acute and chronic wounds, Wundmanagement 2008; 2: 72-80

von Felbert V, Schumann H, Mercer JB, Strasser W, Daeschlein G, Hoffmann G: Therapy of chronic wounds with water-filtered infrared-A (wIRA). Therapie chronischer Wunden mit wassergefiltertem Infrarot A (wIRA). GMS Krankenhaushyg Interdiszip. 2007;2(2):Doc52.
Review Article

Hartel M, Illing P, Mercer JB, Lademann J, Daeschlein G, Hoffmann G: Therapy of acute wounds with water-filtered infrared-A (wIRA)
Therapie akuter Wunden mit wassergefiltertem Infrarot A (wIRA). Review Article. GMS Krankenhaushyg Interdiszip. 2007; 2 (2):Doc53.
Review Article

Hoffmann G: Principles and working mechanisms of water-filtered infrared-A (wIRA) in relation to wound healing.
Grundlagen und Wirkprinzipien von wassergefiltertem Infrarot A (wIRA) in Bezug zur Wundheilung. Review Article. GMS Krankenhaushyg Interdiszip 2007;2(2):Doc54.
Review Article

Gebbers N, Hirt-Burri N, Scaletta C, Hoffmann G, Applegate LA: Water-filtered infrared-A radiation (wIRA) is not implicated in cellular degeneration of human skin. Wassergefilterte Infrarot-A-Strahlung (wIRA) ist nicht an der Zelldegeneration menschlicher Haut beteiligt. GMS Ger Med Sci. 2007;5:Doc08.
Research Article

Voss P, Hajimiragha H, Engels M, Ruhwiedel C, Calles C, Schroeder P, Grune T: Irradiation of GAPDH: a model for environmentally induced protein damage. Biol Chem. 2007; 388(6): 583-92.
Abstract

Hartel M, Hoffmann G, Wente MN, Martignoni ME, Büchler MW, Friess H: Randomized clinical trial of the influence of local water-filtered infrared A irradiation on wound healing after abdominal surgery. Br J Surg. 93(8):952-60. DOI: 10.1002/bjs.5429; 2006.
Abstract

Wundheilungsförderung im MEDICA-Portal
„wIRA fördert Heilung“

Möckel F, Hoffmann G, Obermüller R, Drobnik W, Schmitz G: Influence of water-filtered infrared-A (wIRA) on reduction of local fat and body weight by physical exercise. GMS Ger Med Sci. 2006;4:Doc05
Research Article

Frank S, Menezes S, Lebreton-De Coster C, Oster M, Dubertret L, Coulomb B: Infrared radiation induces the p53 signaling pathway: role in infrared prevention of ultraviolet B toxicity. ExpDermatol. 2006;15(2):130-7.
Abstract

Hoffmann G: Water-filtered infrared A (wIRA) for the improvement of wound healing. Wassergefiltertes Infrarot A (wIRA) zur Verbesserung der Wundheilung. GMS Krankenhaushyg Interdiszip. 2006;1(1)
Übersichtsarbeit

Mercer, J B, de Weerd L: The effect of water-filtered infrared-A (wIRA) irradiation on skin temperature and skin blood flow as evaluated by infrared thermography and scanning laser Doppler imaging. Thermology international 2005; 15: 89-94.

Fuchs M; Fluhr JW; Bankova L, Tittelbach J; Hoffmann G; Elsner P: Photodynamic therapy (PDT) and waterfiltered infrared A (wIRA) in patients with recalcitrant common hand and foot warts. German Medical Science Vol. 2, Doc08, 2004.
Research Article

Burri N., Gebbers N., and Applegate L.A: Chronic infrared-A radiation repair: Implications in cellular senescence and extracellular matrix. In: Pandalai SG, ed. Recent Research Developments in Photochemistry & Photobiology, vol. 7. Trivandrum: Transworld Research Network; 2004. p. 219-31
Online reference

Bräuer A, Weyland W, Kazmaier S, Trostdorf U., Textor Z, Hellige G, Braun U: Efficacy of Postoperative Rewarming after Cardiac Surgery. In: Ann. Thorc. Cardiovasc Surg. Vol. 10 No. 3, 171-177, 2004.

Kelleher DK, Bastian J, Thews O, Vaupel P: Enhanced effects of aminolaevulinic acid-based photodynamic therapy through local hyperthermia in rat tumours. British Journal of Cancer 89: 405-411, 2003.
Abstract

Danno K, Mori N, Toda K, Kobayashi T, Utani A: Near-infrared irradiation stimulates cutaneous wound repair: laboratory experiments on possible mechanisms. Photodermatol Photoimmunol Photomed. 2001;17(6):261-5.
Abstract

Applegate LA, Scaletta C, Panizzon R, Frenk E, Hohlfeld P, Schwarzkopf S: Induction of the putative protective protein ferritin by infrared radiation: Implications in skin repair. International Journal of Molecular Medicine 5: 247-251, 2000
Abstract

Singer D, Schröder M, Harms K: Vorteile der wassergefilterten gegenüber herkömmlicher Infrarot-Strahlung in der Neonatologie. In: Z. Geburtsh. Neonatol 204: 85-92, 2000, Thieme Verlag, Stuttgart, New York

Menezes S, Coulomb B, Lebreton C, Dubertret L: Non-coherent near infrared radiation protects normal human dermal fibroblasts from solar ultraviolet toxicity. J Invest Dermatol. 1998;111(4): 629-33.
Abstract

Vaupel P, Rzeznik J, Stofft E: Wassergefilterte Infrarot-A-Strahlung versus konventionelle Infrarotstrahlung: Temperaturprofile bei lokoregionaler Wärmetherapie. In: Phys rehab Kur Med 5: 77-81, 1995. Abstract im Internet nicht vorhanden.

Hellige G, Becker G, Hahn G: Temperaturverteilung und Eindringtiefe wassergefilterter Infrarot-A-Strahlung. In: Vaupel, P. und Krüger, W. (Hrsg.) Wärmetherapie mit wassergefilterter Infrarot-A-Strahlung, Grundlagen und Anwendungsmöglichkeiten, 2 Auflage: 63-80, 1995, Hippokrates, Stuttgart.
temperaturverteilung-und-eindringtiefe.pdf

Cobarg, CC: Physikalische Grundlagen der wassergefilterterten Infrarot-A-Strahlung. In: Vaupel, P. und Krüger, W. (Hrsg.) Wärmetherapie mit wassergefilterter Infrarot-A-Strahlung, Grundlagen und Anwendungsmöglichkeiten, 2 Auflage: 19-28, 1995, Hippokrates, Stuttgart.
physikalische-grundlagen.pdf

Hoffmann, G: Basics of hyperbaric oxygenation and waterfiltered ultrared-A induced localized hyperthermia in Dermatology. Oxygen Transport to Tissue XV: 181-188, 1994, Plenum Press, New York

Buchmüller, K: Über die ultrarote Emmissionsreflexion und Durchlässigkeit der lebenden menschlichen Haut im Spektralbereich. In: Pflügers Arch. Ges. Physiol.: 272-360, 1961
Hainfeld JF,Lin L, Slatkin DN, Dilmanian FA, Vadas TM, Smilowitz HM. Gold nanoparticlehyperthermia reduces radiotherapy dose. Nanomedicine: Nanotechnology, Biology,and Medicine 2014; in press.

Hainfeld JF,O’Connor MJ, Lin P, Qian L, Slatkin DN, Smilowitz HM: Infrared-Transparent GoldNanoparticles Converted by Tumors to Infrared Absorbers Cure Tumors in Mice byPhotothermal Therapy. PLOS ONE 2014; 9(2): e88414. (DOI:10.1371/journal.pone.0088414)

KuenzliBM, Liebl F, Nuhn PH, Schuster T, Friess H, Hartel M: Impact of Preoperative Local Water-Filtered Infrared-A (wIRA) Irradiation on Postoperative Wound Healing – ARandomized Patient- and Observer Blinded Controlled Clinical Trial. Annals ofSurgery. 2013; 258(6):887-94. (Doi: 10.1097/SLA.0000000000000235)

Al-AhmadA, Tennert C, Karygianni L, Wrbas KT, Hellwig E, Altenburger M: AntimicrobialPhotodynamic therapy using visible light plus water-filtered infrared-A (wIRA).J Med Microbiol 2013; 62,(Pt 3):467-73 (DOI 10.1099/jmm.0.048843-0)

Kelleher D, Piazena H.: The interpretation of clinical studies on the photodynamictreatment of actinic keratosis. Letter to the Editor. GMS Ger Med Sci2012;10:Doc17 (DOI: 10.3205/000168)

Jung T.Grune T: Experimental basis for discriminating between thermal and athermaleffects of water-filtered infrared A irradiation. Ann. N.Y. Acad. Sci. 2012;1259: 33–38
(Doi: 10.1111/j.1749-6632.2012.06581.x)

Knels L.Valtink M. De la Vega Marin J. Steiner G. Roehlecke C. Krueger A. Funk RWH: Effects of temperature and water-filtered infrared-A alone or in combination onhealthy and Glyoxal-stressed fibroblast cultures. Oxidative Medicine andCellular Longevity 2012, Article ID 274953, 8 pages (doi:10.1155/2012/274953)

Heselich A.Frohns F. Frohns A. Naumann, SC. Layer PG: Near-infrared exposure changescellular responses to ionizing radiation. Photochemistry and photobiology 2012;88(1): 135-46. ISSN 1751-1097 (Doi: 10.1111/j.1751-1097.2011.01031.x)

Sulyok I, Fleischmann E, Stift A, Roth G, Lebherz-EichingerD, Kasper D, Spittler A, Kimberger O: Effect of preoperative fever-rangewhole-body hyperthermia on immunological markers in patients undergoingcolorectal cancer surgery. Br J Anaesth. 2012 Nov;109(5):754-61
(doi: 10.1093/bja/aes248.)